Friday, May 11, 2012

Low Carb High Fat Diet Could Replace Dialysis

A type of low-carb, high-fat diet that's typically used to manage seizures for children with epilepsy could reverse kidney disease in Type 1 and Type 2 diabetics, a new animal study suggests.   
If successful in humans, the so-called ketogenic diet could have the potential to replace dialysis, which is a procedure that artificially filters blood in place of a damaged or failed kidney, said study researcher Charles Mobbs, professor of neuroscience and geriatrics and palliative care medicine at Mount Sinai School of Medicine in New York City.
"I speculate that this may be useful to completely cure diabetic kidney failure, and I hope that it's possible," Mobbs told MyHealthNewsDaily. "If it's possible, we can potentially not require dialysis. That's a big deal."
However, a lot more research in mice is needed before any studies can be done in humans, Mobbs said, let alone determine if the diet can reverse advanced kidney disease in humans, he said.
"That's the first thing we want to establish in mice: Can we truly reset the clock? Can we completely correct the [kidney] impairments?" Mobbs said.
Other experts say the finding is promising for Type 1 and Type 2 diabetics with earlier-stage kidney disease, but more research must be done to provide evidence that the diet can make an impact on end-stage kidney disease, or kidney failure.
Type 1 diabetes is a chronic disease that occurs when the pancreas cannot produce enough insulin (needed to move blood sugar into cells for energy) to control blood sugar levels, according to the National Institutes of Health. Type 2 diabetes occurs when the body becomes resistant to insulin, leading to high blood sugar levels. Overweight and obesity, a sedentary lifestyle and poor diet are risk factors for Type 2 diabetes, according to the NIH.
The study was published today (April 20) in

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